Clinical performance

NIPT by Life Genomics is a simple, safe and accurate non-invasive prenatal test for detecting trisomies 13, 18 and with high a sensitivity and specificity.

Performance based on clinical validation performed at Life Genomics, Gothenburg, Sweden.

Syndrome

Trisomy 21

Trisomy 18

Trisomy 13

Rare autosomal aneuploidies

CNV

Fetal sex

Sensitivity

>99.9%

94.12%

95.45%

>99.9%

98.92% concordance

Specificity

99.75%

99.92%

>99.9%

99.52%

97.66%

N/A

PPV

96.05%

96.43%

>99.9%

77.78%

38.30%

N/A

Sex Chromosome Aneuploidies

SCAs (combined)

Sensitivity

97.78%

PPV

91.67%

NPV

99.92%

Note that no NIPT method is 100% either in terms of sensitivity or specificity.
NIPT always risks picking up abnormalities that only affect the placenta, and not the fetus.